Shc(Phospho-Tyr317) Rabbit Polyclonal Antibody, 100ul Multiplex Immunoassays • Five rotors with 0

• Five rotors with 0

This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X)

Huntington's disease and temporal lobe epilepsy

56kDa and 31kDa

an important hormone and neurotransmitter

Shc(Phospho-Tyr317) Rabbit Polyclonal Antibody, 100ul Multiplex Immunoassays • Five rotors with 0This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms p52Shc and p46Shc link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike