RUBIC Rabbit Polyclonal Antibody, 50ul Transporters This member contains six membrane-spanning

This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment

Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect

it deacetylates p53 and modulates its effect on cell growth and apoptosis

Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function

which regulates sister chromatid cohesion and recombination between homologous chromosomes

RUBIC Rabbit Polyclonal Antibody, 50ul Transporters This member contains six membrane-spanningThe protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains an N terminal RUN domain and a C terminal DUF4206 domain. The RUN domain is involved in Ras like GTPase signaling and the DUF4206 domain contains a diacylglycerol (DAG) binding like motif. Mutation in this gene results in deletion of the DAG binding like motif and causes a