IGF-IR(Phospho Tyr1161) Polyclonal Antibody, 20ul[BT-AP08809] Culture Plate Inserts ALX3 encodes a nuclear protein

ALX3 encodes a nuclear protein (ALX homeobox 3) with a homeobox DNA-binding domain that functions as a transcriptional regulator involved in cell-type differentiation and development

while decreased activity leads to hypofibrinolysis

Eukaryotic gene transcription is regulated by sequence-specific transcription factors that bind modular cis acting promoter and enhancer elements

An important paralog of this gene is CDK14

which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids

IGF-IR(Phospho Tyr1161) Polyclonal Antibody, 20ul[BT-AP08809] Culture Plate Inserts ALX3 encodes a nuclear proteinThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have