TRPM7 Polyclonal Antibody, 20ul Live Cell Imaging Mutations in NODAL are associated

Mutations in NODAL are associated with heterotaxy

see MIM 609700) and GTPase-activating proteins (GAPs)

Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30)

and expression of this gene may be altered in tumors

This gene encodes a member of the carboxylesterase large family

TRPM7 Polyclonal Antibody, 20ul Live Cell Imaging Mutations in NODAL are associatedThe protein encoded by this gene is both an ion channel and a serine threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. Defects in this gene are a cause of amyotrophic lateral sclerosis parkinsonism dementia complex of Guam. Alternative splicing of this gene results in multiple transcript variants.