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Caspase-3 Polyclonal Antibody, 50ul[BT-AP01203] Lysosome Granzyme H is reported to

SKU: 33458237347

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Caspase-3 Polyclonal Antibody, 50ul[BT-AP01203] Lysosome Granzyme H is reported toCASP3 encodes a protein which is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein (caspase 3) cleaves and activates caspases 6, 7 and 9,

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Description

Granzyme H is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells

RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor

|Belongs to the DNA polymerase type-X family

a complex involved in DNA double-strand breaks by homologous recombination

Inhibition of the encoded protein can lead to apoptosis

Caspase-3 Polyclonal Antibody, 50ul[BT-AP01203] Lysosome Granzyme H is reported toCASP3 encodes a protein which is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein (caspase 3) cleaves and activates caspases 6, 7 and 9,

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