Smad1(Phospho Ser465) Polyclonal Antibody, 20ul Low retention tips Mutations in this gene have

Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG)

Following cleavage| the mature protein translocates to the nucleus and activates transcription by binding to the SRE1

though there are conflicting reports of such linkages in other populations

called receptor (calcitonin) activity modifying proteins (RAMPs)

This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse

Smad1(Phospho Ser465) Polyclonal Antibody, 20ul Low retention tips Mutations in this gene haveThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell