Cytokeratin 18(Phospho Ser52) Polyclonal Antibody, 100ul In vitro Assessment and angiogenesis

and angiogenesis

May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53

as well as glycogen synthesis and glucose uptake

Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration

The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest| and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells

Cytokeratin 18(Phospho Ser52) Polyclonal Antibody, 100ul In vitro Assessment and angiogenesisKRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.