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ZO-2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases Through interaction with the ERBB

SKU: 32889662343

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ZO-2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases Through interaction with the ERBBTJP2 (tight junction protein 2) encodes a zonula occluden that is a member of the membrane associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in TJP2 have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal

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Description

Through interaction with the ERBB family of receptors

This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation

Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor

The CCR4-NOT complex plays a role in many cellular processes| including miRNA-mediated repression| mRNA degradation| and transcriptional regulation

A highly-similar gene encoding a related protein is also found on chromosome 1

ZO-2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases Through interaction with the ERBBTJP2 (tight junction protein 2) encodes a zonula occluden that is a member of the membrane associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in TJP2 have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal

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