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p53 (Di Methyl Lys370) Polyclonal Antibody, 100ul Bottles A CCTG expansion from <30

SKU: 32766421182

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EUR141.00 EUR173.00

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p53 (Di Methyl Lys370) Polyclonal Antibody, 100ul Bottles A CCTG expansion from <30TP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. Tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome. Alternative

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Description

A CCTG expansion from <30 repeats to 75-11000 repeats in the first intron of this gene results in myotonic dystrophy type 2

function in intracellular transport

Epigenetic silencing of this gene has been observed in gliomas

orexin A and orexin B

It also plays an important role in stress fiber formation

p53 (Di Methyl Lys370) Polyclonal Antibody, 100ul Bottles A CCTG expansion from <30TP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. Tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome. Alternative

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