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MLK1/2 Polyclonal Antibody, 50ul Lentiviral Packaging Mutations in this gene have

SKU: 32731684709

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MLK1/2 Polyclonal Antibody, 50ul Lentiviral Packaging Mutations in this gene haveThe protein encoded by MAP3K10 is a member of the serine threonine kinase family. This kinase has been shown to activate MAPK8 JNK and MKK4 SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.

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Description

Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC)

This nuclear gene encodes polypeptide 1 (muscle isoform) of subunit VIIa and the polypeptide 1 is present only in muscle tissues

NCP proteins mediate neuron-glial interactions in vertebrates and glial-glial contact in invertebrates

a consensus furin cleavage site

The enzyme has widespread tissue expression and has a role in metabolism

MLK1/2 Polyclonal Antibody, 50ul Lentiviral Packaging Mutations in this gene haveThe protein encoded by MAP3K10 is a member of the serine threonine kinase family. This kinase has been shown to activate MAPK8 JNK and MKK4 SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.

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