Gamma Tubulin mouse Monoclonal Antibody(7B1), 100ul sgRNA Library Construction Disruption of WWOX is also

Disruption of WWOX is also associated with autosomal recessive spinocerebellar ataxia 12

Following cleavage| the mature protein translocates to the nucleus and activates transcription by binding to the SRE1

making it unable to perform endocytosis

occupying less than 650 kb combined

it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins

Gamma Tubulin mouse Monoclonal Antibody(7B1), 100ul sgRNA Library Construction Disruption of WWOX is alsoThis gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7.