STXB2 Rabbit Polyclonal Antibody, 20ul Subcellular Fractions which suggests a regulatory role

which suggests a regulatory role in DNA replication during the S-phase of the cell cycle

It is expressed by hepatocytes

mediator complex subunit 12 (MED12)

and thus help maintain the structural organization of the nuclear envelope

Members of this protein family contain ten conserved cysteine residues that form intra-molecular disulfide bonds

STXB2 Rabbit Polyclonal Antibody, 20ul Subcellular Fractions which suggests a regulatory roleThis gene encodes a member of the STXBP unc 18 SEC1 family. The encoded protein is involved in intracellular trafficking control of SNARE (soluble NSF attachment protein receptor) complex assembly and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.