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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 20ul Insect Expression MED8 encodes a protein component

SKU: 31880263155

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MDM2(Phospho Ser186/S188) Polyclonal Antibody, 20ul Insect Expression MED8 encodes a protein componentThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

MED8 encodes a protein component of the mediator complex

including non-Hodgkin lymphoma

which then activates a specific MAPK

these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues)

The arachidonate 5-lipoxygenasen

MDM2(Phospho Ser186/S188) Polyclonal Antibody, 20ul Insect Expression MED8 encodes a protein componentThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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