Tie2(Phospho-Tyr992) Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis Mitogen-activated protein kinase kinase kinase

Mitogen-activated protein kinase kinase kinase 7 encoded by MAP3K7 is a member of the serine/threonine protein kinase family

is associated with a milder form of the disorder called van Buchem disease

bone resorption

Mutations have been associated with X-linked dyskeratosis congenita

Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16

Tie2(Phospho-Tyr992) Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis Mitogen-activated protein kinase kinase kinaseThis gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin like domains three epidermal growth factor (EGF) like domains and three fibronectin type III repeats. The ligand angiopoietin 1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with