Rad17 Polyclonal Antibody, 100ul[BT-AP07600] 3D Cell Culture Consumables Cyclin D1 has been shown

Cyclin D1 has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb

This gene is part of a cluster of similar genes on chromosome 3

Four alternatively spliced transcript variants encoding distinct isoforms have been described

C6ORF55 encodes a protein involved in trafficking of the multivesicular body| an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes (Ward et al

TAF5 encodes an integral subunit of TFIID associated with all transcriptionally competent forms of that complex

Rad17 Polyclonal Antibody, 100ul[BT-AP07600] 3D Cell Culture Consumables Cyclin D1 has been shownThe protein encoded by RAD17 (RAD17 checkpoint clamp loader component) is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint