E2F-3 (Acetyl-Lys168) Polyclonal Antibody, 100ul Fluorescent Staining Other members of this small

Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes

This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins

some of which are associated with Creutzfeldt-Jakob disease

Defects in PRF1 cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2)

The encoded protein binds directly to retinoblastoma protein

E2F-3 (Acetyl-Lys168) Polyclonal Antibody, 100ul Fluorescent Staining Other members of this smallE2F3 (E2F transcription factor 3) encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are