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Raf-1(Phospho Ser289) Polyclonal Antibody, 100ul Glassware Deletions of this gene locus

SKU: 31501654458

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Raf-1(Phospho Ser289) Polyclonal Antibody, 100ul Glassware Deletions of this gene locusThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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Description

Deletions of this gene locus are found in various types of carcinomas

DSCR3 is expressed in most tissues examined

It also may play a role in regulating the kinetics of signaling in the phototransduction cascade

The protein encoded by C1QBP is known to bind to the globular heads of C1q molecules and inhibit C1 activation

increase blood flow

Raf-1(Phospho Ser289) Polyclonal Antibody, 100ul Glassware Deletions of this gene locusThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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