ATR Polyclonal Antibody, 50ul Centrifuges Defects in this gene are

Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome

CDC25B (cell division cycle 25B) is a member of the CDC25 family of phosphatases

RAD52 homolog

which is required for production of the sex hormones

The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein

ATR Polyclonal Antibody, 50ul Centrifuges Defects in this gene areThe protein encoded by ATR (ATR serine threonine kinase) belongs the PI3 PI4 kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1,