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Rb(Phospho Ser795) Polyclonal Antibody, 100ul Cryogenic Vials May contribute to signal transduction

SKU: 31380667635

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Rb(Phospho Ser795) Polyclonal Antibody, 100ul Cryogenic Vials May contribute to signal transductionThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

May contribute to signal transduction through its intracellular domain

and the counterbalancing phosphatase

This gene encodes a member of the G-protein-coupled receptor 1 family

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CDH2 encodes a classical cadherin and member of the cadherin superfamily

Rb(Phospho Ser795) Polyclonal Antibody, 100ul Cryogenic Vials May contribute to signal transductionThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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