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VPS35 Polyclonal Antibody, 50ul Insect Expression Lambda 5 is critical for

SKU: 31311600967

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VPS35 Polyclonal Antibody, 50ul Insect Expression Lambda 5 is critical forVPS35 (VPS35, retromer complex component) belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and

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Description

Lambda 5 is critical for B cell development in mammals

The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks

The tail domain binds to the cytoplasmic domain of both integrin beta-1a and beta-1d isoforms

28S ribosomal protein S35 mitochondrial (mitochondrial ribosomal protein S35) is encoded by nuclear genes MRPS35 and help in protein synthesis within the mitochondrion

Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses

VPS35 Polyclonal Antibody, 50ul Insect Expression Lambda 5 is critical forVPS35 (VPS35, retromer complex component) belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and

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