Shc(Phospho Tyr427) Polyclonal Antibody, 20ul Biomatrix for 15mLx16

for 15mLx16

Mutations in this gene may be associated with atrial fibrillation

It is an adaptor protein localized in the nucleus

The protein functions as a regulator of RNA polymerase II-mediated transcription through elongation and chromatin remodeling functions

Histone deacetylase 4 encoded by HDAC4 belongs to class II of the histone deacetylase/acuc/apha family

Shc(Phospho Tyr427) Polyclonal Antibody, 20ul Biomatrix for 15mLx16This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation.