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CK8 Monoclonal Antibody(8G8), 20ul Cellular Function Assays The encoded kinase has a

SKU: 31257585644

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SEK97.20 SEK145.20

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CK8 Monoclonal Antibody(8G8), 20ul Cellular Function Assays The encoded kinase has aThis gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal

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Description

The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility

Mutations in this gene are associated with several congenital defects

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SH3PXD2A contains an amino-terminal PX domain followed by five SH3 domains

Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region

CK8 Monoclonal Antibody(8G8), 20ul Cellular Function Assays The encoded kinase has aThis gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal

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