HLAG Polyclonal Antibody, 20ul Biomatrix There are six pseudogenes of

There are six pseudogenes of this gene found on chromosomes 2

The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance

Variations in this protein's sequence have been implicated in Alzheimer's disease

the multiplicity of the genes is attributed to successive gene duplication events

Based on their distribution patterns

HLAG Polyclonal Antibody, 20ul Biomatrix There are six pseudogenes ofHLA G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. HLA G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide,