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Rac GAP1 Polyclonal Antibody, 100ul[BT-AP07591] Cell Dissociation and may also be involved

SKU: 3111172381

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Rac GAP1 Polyclonal Antibody, 100ul[BT-AP07591] Cell Dissociation and may also be involvedRACGAP1 encodes a GTPase activating protein (GAP) that is a compoment of the centralspindlin complex. Rac GTPase activating protein 1 binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho mediated signals. Rac GTPase activating protein 1 plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for RACGAP1. There is a

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Description

and may also be involved in hematopoietic development and differentiation

The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases

at cell-cell epithelial junctions

and is induced by transforming growth factor-beta (TGF-beta) to repress TGF-beta receptor II gene expression

This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites

Rac GAP1 Polyclonal Antibody, 100ul[BT-AP07591] Cell Dissociation and may also be involvedRACGAP1 encodes a GTPase activating protein (GAP) that is a compoment of the centralspindlin complex. Rac GTPase activating protein 1 binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho mediated signals. Rac GTPase activating protein 1 plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for RACGAP1. There is a

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