MSK1(Phospho Ser212) Polyclonal Antibody, 100ul Oligo Pool Mutations in this gene are

Mutations in this gene are been associated with X-linked mental retardation

and these opposite actions are thought to be mediated by two classes of receptors

This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein

induction:By tumor necrosis factor alpha (TNFalpha)

Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity

MSK1(Phospho Ser212) Polyclonal Antibody, 100ul Oligo Pool Mutations in this gene areCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,cofactor: Magnesium.,enzyme regulation: Appears to be activated by multiple phosphorylations on threonine and serine residues. ERK1 2 and MAPK14 p38 alpha may play a role in this process.,Serine threonine kinase required for the mitogen or stress induced phosphorylation of the transcription factors CREB (cAMP response element binding protein) and ATF1 (activating transcription factor 1).