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DAB2 Rabbit Polyclonal Antibody, 50ul Cellular Cultivation & Health Management which affect the highly conserved

SKU: 30793485015

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DAB2 Rabbit Polyclonal Antibody, 50ul Cellular Cultivation & Health Management which affect the highly conservedThis gene encodes a mitogen responsive phosphoprotein. It is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2 an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras) via its C terminal proline rich sequences and may thus modulate growth factor Ras

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Description

which affect the highly conserved carbohydrate recognition domain

they function in the formation of the right ventricle and aortic arch arteries

SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested

The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family

A nonconventional nuclear localization sequence (NLS) has been found for protein kinase cAMP-dependent type I regulatory subunit alpha which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40)

DAB2 Rabbit Polyclonal Antibody, 50ul Cellular Cultivation & Health Management which affect the highly conservedThis gene encodes a mitogen responsive phosphoprotein. It is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2 an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras) via its C terminal proline rich sequences and may thus modulate growth factor Ras

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