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Artn Polyclonal Antibody, 50ul Mammalian Expression Transcript variants utilizing alternative polyadenylation

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Artn Polyclonal Antibody, 50ul Mammalian Expression Transcript variants utilizing alternative polyadenylationThis gene encodes a secreted ligand of the glial cell line derived neurotrophic factor (GDNF) subfamily and TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer.

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Description

Transcript variants utilizing alternative polyadenylation signals exist for this CTSG

The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase

as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al

Alternative transcript variants encoding distinct isoforms have been described

Two transcript variants encoding two different isoforms have been found for APOL4

Artn Polyclonal Antibody, 50ul Mammalian Expression Transcript variants utilizing alternative polyadenylationThis gene encodes a secreted ligand of the glial cell line derived neurotrophic factor (GDNF) subfamily and TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer.

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