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Krs-1/2 Polyclonal Antibody, 50ul RNA Synthesis A pseudogene of this gene

SKU: 29469679722

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Krs-1/2 Polyclonal Antibody, 50ul RNA Synthesis A pseudogene of this geneSTK3 (serine threonine kinase 3) encodes a serine threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C terminal portion. The N terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants

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Description

A pseudogene of this gene is located on the long arm of chromosome 8

Freeman-Sheldon syndrome and Sheldon-Hall syndrome

it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters

and is involved in IL-31 signaling via activation of STAT-3 and STAT-5

Binds to and inhibits cyclin-dependent kinase activity| preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression

Krs-1/2 Polyclonal Antibody, 50ul RNA Synthesis A pseudogene of this geneSTK3 (serine threonine kinase 3) encodes a serine threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C terminal portion. The N terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants

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