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RAB21 Polyclonal Antibody, 20ul Cell Labeling & Imaging Defects in this gene appear

SKU: 29190862037

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RAB21 Polyclonal Antibody, 20ul Cell Labeling & Imaging Defects in this gene appearThis gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by

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Description

Defects in this gene appear to be a cause of various types of leukemia or lymphoma

while having certain extent of redundancy

and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function

The telomeric and centromeric copies of this gene are nearly identical and encode the same protein

Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini

RAB21 Polyclonal Antibody, 20ul Cell Labeling & Imaging Defects in this gene appearThis gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by

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