CD180 Polyclonal Antibody, 100ul Immunology The basic helix-loop-helix (bHLH) family

The basic helix-loop-helix (bHLH) family of transcription factors play roles in a variety of developmental and adult biological settings

A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis

A similar duplicated gene is located next to this gene on chromosome 16

While other members of this family are found throughout vertebrates

thymus and fetal liver

CD180 Polyclonal Antibody, 100ul Immunology The basic helix-loop-helix (bHLH) familyCD180 is a cell surface molecule consisting of extracellular leucine rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD 1 and form the cell surface receptor complex, RP105 MD 1. It belongs to the family of pathogen receptors, Toll like receptors (TLR). RP105 MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of