P2X3 Polyclonal Antibody, 50ul Proteases The N-terminal PDZ domain of

The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1

The encoded protein acts as a nuclear transcription factor

inflammatory bowel disease

which regulate their target genes upon binding of cognate response elements

ADRA2B encodes a seven-pass transmembrane protein

P2X3 Polyclonal Antibody, 50ul Proteases The N-terminal PDZ domain ofThe product of P2RX3 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand gated ion channel and may transduce ATP evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in