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Phospho-5-LO (S523) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) The cyclin dependent kinase 20

SKU: 28878052509

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Phospho-5-LO (S523) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) The cyclin dependent kinase 20ALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5 lipoxygenasen, which is expressed specifically in bone marrow derived cells, catalyzes the conversion of arachidonic acid to 5(S) hydroperoxy 6 trans 8,11,14 cis eicosatetraenoic acid, and further to the allylic epoxide 5(S) trans 7,9 trans 11,14 cis eicosatetrenoic acid (leukotriene A4). Leukotrienes

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Description

The cyclin dependent kinase 20 encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases

and hence neuronal excitability

The variation of this locus may affect the development of alcohol-related problems

CAPN10 is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM)

and may regulate cyclosporine A-mediated immunosuppression

Phospho-5-LO (S523) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) The cyclin dependent kinase 20ALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5 lipoxygenasen, which is expressed specifically in bone marrow derived cells, catalyzes the conversion of arachidonic acid to 5(S) hydroperoxy 6 trans 8,11,14 cis eicosatetraenoic acid, and further to the allylic epoxide 5(S) trans 7,9 trans 11,14 cis eicosatetrenoic acid (leukotriene A4). Leukotrienes

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