c-Fms(Phospho Tyr561) Polyclonal Antibody, 50ul Molecular Biology This gene encodes a member

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR)

Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia

Two alternately spliced transcripts encoding two protein isoforms have been identified

PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes

Implicated in endocytosis

c-Fms(Phospho Tyr561) Polyclonal Antibody, 50ul Molecular Biology This gene encodes a memberThe protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1 PDGF