Huntingtin(Phospho Ser421) Polyclonal Antibody, 50ul Proteases As a scaffold protein involved

As a scaffold protein involved in cell polarization processes| this protein binds to many other proteins

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Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II)

Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues

a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1

Huntingtin(Phospho Ser421) Polyclonal Antibody, 50ul Proteases As a scaffold protein involvedHuntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range of trinucleotide repeats (9 35) has been identified in normal controls, and repeat numbers in excess of 40 have been described as