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Ret Polyclonal Antibody, 50ul[BT-AP07760] Peripheral Blood Separation Tube PDIA3 encodes a protein of

SKU: 27927462659

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SEK162.00 SEK195.00

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Ret Polyclonal Antibody, 50ul[BT-AP07760] Peripheral Blood Separation Tube PDIA3 encodes a protein ofRET, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine

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Description

PDIA3 encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins

and thermoregulation

The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel

This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites

disease:Antibodies against RIP11 are found in sera from patients with systemic lupus erythematosus (SLE) or Sjoegren syndrome (SS)

Ret Polyclonal Antibody, 50ul[BT-AP07760] Peripheral Blood Separation Tube PDIA3 encodes a protein ofRET, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine

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