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MRGX2 Polyclonal Antibody, 20ul Antibody Development The galectins have been implicated

SKU: 27475266261

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MRGX2 Polyclonal Antibody, 20ul Antibody Development The galectins have been implicatedOrphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and or development, including the sensation or modulation of pain. Cortistatin 14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor expressing cells, cortistatin stimulated increases in intracellular Ca(2+)

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Description

The galectins have been implicated in many essential functions including development

contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane

As a scaffold protein involved in cell polarization processes| this protein binds to many other proteins

ERCC5 encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage

This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA)

MRGX2 Polyclonal Antibody, 20ul Antibody Development The galectins have been implicatedOrphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and or development, including the sensation or modulation of pain. Cortistatin 14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor expressing cells, cortistatin stimulated increases in intracellular Ca(2+)

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