MYH Polyclonal Antibody, 100ul Stepper KPNA2 (karyopherin subunit alpha 2)
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MYH Polyclonal Antibody, 100ul Stepper KPNA2 (karyopherin subunit alpha 2)MUTYH encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8 oxo 7,8 dihydroguanine, a major oxidatively damaged DNA lesion. A G specific adenine DNA glycosylase is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple
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