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CBX2 Polyclonal Antibody, 100ul Cellular Function Assays Mutations in ADIPOQ are associated

SKU: 26939115877

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SEK123.75 SEK171.75

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CBX2 Polyclonal Antibody, 100ul Cellular Function Assays Mutations in ADIPOQ are associatedCBX2 (chromobox 2) encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of CBX2 in mice results in male to female gonadal sex reversal. Mutations in CBX2 are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms

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Description

Mutations in ADIPOQ are associated with adiponectin deficiency

The exact function of Staufen homolog 2 is not known| but since it contains 3 copies of conserved dsRNA binding domain| it could be involved in double-stranded RNA binding events

This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA

C17 is a cytokine-like protein specifically expressed in bone marrow and cord blood mononuclear cells that bear the CD34 (MIM 142230) surface marker

and some types of T-cells

CBX2 Polyclonal Antibody, 100ul Cellular Function Assays Mutations in ADIPOQ are associatedCBX2 (chromobox 2) encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of CBX2 in mice results in male to female gonadal sex reversal. Mutations in CBX2 are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms

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