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IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 100ul Vacuum Filter and cell migration

SKU: 26279188946

4.9
EUR123.75 EUR154.75

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IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 100ul Vacuum Filter and cell migrationThis gene encodes a member of the NF kappa B inhibitor family which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

and cell migration

chromatin structure and gene expression

This protein has been shown to be up-regulated in tumors| especially in breast tumors| and thus it is associated with tumor invasiveness

Pseudogenes corresponding to this gene are found on chromosomes 3p

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IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 100ul Vacuum Filter and cell migrationThis gene encodes a member of the NF kappa B inhibitor family which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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