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CBX8 Polyclonal Antibody, 50ul Sampling Tubes The ligand binding of this

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CBX8 Polyclonal Antibody, 50ul Sampling Tubes The ligand binding of thisComponent of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys 119', rendering chromatin heritably changed in its expressibility.,Contains 1 chromo domain.,subunit: Component of chromatin

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Description

The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules

approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene

and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions

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In addition| the encoded protein interacts with LIS1| the regulatory gamma subunit of platelet activating factor acetylhydrolase| and this interaction is important to proper microtubule function in the developing cortex

CBX8 Polyclonal Antibody, 50ul Sampling Tubes The ligand binding of thisComponent of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys 119', rendering chromatin heritably changed in its expressibility.,Contains 1 chromo domain.,subunit: Component of chromatin

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