OR1G1 Polyclonal Antibody, 50ul Contamination Detection & Removal The pleckstrin homology and RhoGEF

The pleckstrin homology and RhoGEF domain containing G4 encoded by PLEKHG4 can function as a guanine nucleotide exchange factor (GEF) and may play a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus

These proteins form the Polycomb repressive complexes which are involved in transcriptional repression

Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons

benign Warthin tumors and clear cell hidradenomas

This suggests this gene product may function as a tumor suppressor

OR1G1 Polyclonal Antibody, 50ul Contamination Detection & Removal The pleckstrin homology and RhoGEFOlfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G protein coupled receptors (GPCR) arising from single coding exon genes. Olfactory receptors share a 7 transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein mediated