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Rb Polyclonal Antibody, 20ul[BT-AP07694] Immuno Plates with cell adhesion molecules

SKU: 25321043300

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Rb Polyclonal Antibody, 20ul[BT-AP07694] Immuno Plates with cell adhesion moleculesThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

with cell adhesion molecules

Studies of the similar gene in mouse suggested that this protein may interact with

which in turn activates MAPK

Acts by interacting with the second WW domain of ITCH

The protein encoded by DYSF (dysferlin) belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma

Rb Polyclonal Antibody, 20ul[BT-AP07694] Immuno Plates with cell adhesion moleculesThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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