TP53INP2 Polyclonal Antibody, 100ul[BT-AP09143] Variant Libraries |disease:A chromosomal aberration involving NFKB2

|disease:A chromosomal aberration involving NFKB2 is found in a cutaneous T-cell leukemia (C-TCL) cell line

This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis

Intracellularly

The activity of the protein is negatively regulated by its SH3 domain

The encoded protein interacts with TP53

TP53INP2 Polyclonal Antibody, 100ul[BT-AP09143] Variant Libraries |disease:A chromosomal aberration involving NFKB2The protein encoded by TP53INP2 (tumor protein p53 inducible nuclear protein 2) promotes autophagy and is essential for proper autophagosome formation and processing. In addition, the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1 RNA polymerase I preinitiation complex. Finally, this protein serves as a transcriptional activator for some genes.