PIGR Polyclonal Antibody, 100ul Reagent Reservoirs An isoform lacking exon 6

An isoform lacking exon 6 has been shown to play a role in the cohesion of centrioles (PMID: 16582621 and PMID: 18331714)

and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators

and may function in the apoptotic pathway

The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP)| a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD)

RIMKLA contains one ATP-grasp domain and binds two manganese ions per subunit

PIGR Polyclonal Antibody, 100ul Reagent Reservoirs An isoform lacking exon 6This gene is a member of the immunoglobulin superfamily. The encoded poly Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.