PLB Polyclonal Antibody, 100ul Immunology Expression of this gene is

Expression of this gene is almost exclusively in the brain

Pseudogenes of this gene have been defined on chromosomes 14 and 17

and it therefore likely functions in spermatid formation

possibly acting as the signal that turns on the membrane fusion machinery

The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini

PLB Polyclonal Antibody, 100ul Immunology Expression of this gene isThe protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the