MVK Polyclonal Antibody, 100ul Molecular Biology The protein encoded by this

The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I

Tetramer composition varies depending on tissue type

Histone H3

and a 153 aa cytoplasmic region

has been associated with acute myelomonocytic leukemia

MVK Polyclonal Antibody, 100ul Molecular Biology The protein encoded by thisMVK encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of MVK results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever