Rat E3 Ubiquitin-protein Ligase Trim63, TRIM63 ELISA Kit, 96T Mammalian Expression The gene product interacts with

The gene product interacts with certain inflammatory response factors| and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease

This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins

PubMed: 23699523

The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6

A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia

Rat E3 Ubiquitin-protein Ligase Trim63, TRIM63 ELISA Kit, 96T Mammalian Expression The gene product interacts withE3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I TNNI3 and probably of other sarcomeric