p53 Rabbit Polyclonal Antibody, 100ul[BT-AP11724] Pipette Controller Binding and activation of the

Binding and activation of the receptor stimulates Janus protein kinases

Alternative splicing results in multiple transcript variants encoding different protein isoforms

Three transcript variants| one protein-coding and the other two non-protein coding| have been found for this gene

Expression of this gene is regulated by sterol regulatory element-binding proteins| transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids

The DNA repair protein complementing XP-A cells is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens

p53 Rabbit Polyclonal Antibody, 100ul[BT-AP11724] Pipette Controller Binding and activation of theThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative