DCMC Rabbit Polyclonal Antibody, 20ul Custom DNA Oligos It is located close to

It is located close to translocation breakpoints associated with premature ovarian failure

Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling

a heavy catalytic subunit and a light regulatory subunit

Translation of this protein is initiated at a non-AUG (AUA) start codon

This gene appears to represent an intronless retrocopy of a related multi-exon gene located on chromosome 9

DCMC Rabbit Polyclonal Antibody, 20ul Custom DNA Oligos It is located close toThe product of this gene catalyzes the breakdown of malonyl CoA to acetyl CoA and carbon dioxide. Malonyl CoA is an intermediate in fatty acid biosynthesis and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria peroxisomes and the cytoplasm. Mutations in this gene result in malonyl CoA decarboyxlase deficiency.