PEG10 Monoclonal Antibody, 50ul[BT-MCA1017] Recombinant Protein Expression The protein encoded by PKN1

The protein encoded by PKN1 (protein kinase N1) belongs to the protein kinase C superfamily

Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization

This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane

this protein does not interact with RASGAP

and it is therefore considered to be a therapeutic target

PEG10 Monoclonal Antibody, 50ul[BT-MCA1017] Recombinant Protein Expression The protein encoded by PKN1This is a paternally expressed imprinted gene that is thought to have been derived from the Ty3 Gypsy family of retrotransposons. It contains two overlapping open reading frames, RF1 and RF2, and expresses two proteins: a shorter, gag like protein (with a CCHC type zinc finger domain) from RF1 and a longer, gag pol like fusion protein (with an additional aspartic protease motif) from RF1 RF2 by 1 translational frameshifting ( 1 FS). While 1 FS has